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Showing 1 to 12 of 760 entries
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Effect of storage time, postmortem interval, agonal state, and gender on the postmortem preservation of glial fibrillary acidic protein and oxidatively damaged proteins in human brains.

Biopreservation and biobanking

Harish G, Venkateshappa C, Mahadevan A, Pruthi N, Bharath MM, Shankar SK.
PMID: 24836634
Biopreserv Biobank. 2011 Dec;9(4):379-87. doi: 10.1089/bio.2011.0033. Epub 2011 Nov 10.

Biochemical analyses of many brain diseases have highlighted that oxidative damage of proteins and astrogliosis are important events associated with pathology. However, human studies on the status of protein oxidation/nitration and astrogliosis [indicated by expression of glial fibrillary acidic...

Universal Scale of Intelligence Estimates (USIE): Representing Intelligence Estimated From Level of Education.

Assessment

de Vent NR, Agelink van Rentergem JA, Kerkmeer MC, Huizenga HM, Schmand BA, Murre JMJ.
PMID: 27402658
Assessment. 2018 Jul;25(5):557-563. doi: 10.1177/1073191116659133. Epub 2016 Jul 07.

In clinical neuropsychology, it is often necessary to estimate a patient's premorbid level of cognitive functioning in order to evaluate whether his scores on cognitive tests should be considered abnormal. In practice, test results from before the onset of...

Reply to the letter of Susan Staugaitis.

Brain pathology (Zurich, Switzerland)

Thom M.
PMID: 27324726
Brain Pathol. 2016 Nov;26(6):788. doi: 10.1111/bpa.12400.

No abstract available.

Mini-Symposium: Energy Demand and Energy Supply in Alzheimer's Disease - Introduction.

Brain pathology (Zurich, Switzerland)

Moreira PI.
PMID: 27327396
Brain Pathol. 2016 Sep;26(5):606. doi: 10.1111/bpa.12398.

No abstract available.

Elevated Levels of Proinflammatory Cytokines in Cerebrospinal Fluid of Multiple Sclerosis Patients.

Frontiers in immunology

Khaibullin T, Ivanova V, Martynova E, Cherepnev G, Khabirov F, Granatov E, Rizvanov A, Khaiboullina S.
PMID: 28572801
Front Immunol. 2017 May 18;8:531. doi: 10.3389/fimmu.2017.00531. eCollection 2017.

Multiple sclerosis (MS) is an autoimmune neurodegenerative disease characterized by chronic brain inflammation. Leukocyte infiltration of brain tissue causes inflammation, demyelination, and the subsequent formation of sclerotic plaques, which are a hallmark of MS. Activation of proinflammatory cytokines is...

Haemodynamic response associated with both ictal and interictal epileptiform activity using simultaneous video electroencephalography/near infrared spectroscopy in a within-subject study.

Journal of near infrared spectroscopy

Monrad P, Sannagowdara K, Bozarth X, Bhosrekar S, Hecox K, Nwosu M, Schwabe M, Meyer M, Szabo A, Prigge J, Lemke R, Horn B, Whelan HT.
PMID: 26538840
J Near Infrared Spectrosc. 2015;23(4):209-218. doi: 10.1255/jnirs.1170. Epub 2015 Sep 24.

This paper reports the findings from a pilot study of four patients with medically refractory epilepsy undergoing pre-surgical evaluation with ages ranging from 5 to 17 years. Video electroencephalography recordings and data from a near infrared spectroscopy cerebral/somatic oximeter...

Population-based analysis of pathological correlates of dementia in the oldest old.

Annals of clinical and translational neurology

Tanskanen M, Mäkelä M, Notkola IL, Myllykangas L, Rastas S, Oinas M, Lindsberg PJ, Polvikoski T, Tienari PJ, Paetau A.
PMID: 28275649
Ann Clin Transl Neurol. 2017 Feb 12;4(3):154-165. doi: 10.1002/acn3.389. eCollection 2017 Mar.

OBJECTIVE: The aim of this study was to analyze brain pathologies which cause dementia in the oldest old population.METHODS: All 601 persons aged ≥85 years living in the city of Vantaa (Finland), on April 1st, 1991 formed the study...

Autosomal Dominant Alzheimer Disease: A Unique Resource to Study CSF Biomarker Changes in Preclinical AD.

Frontiers in neurology

Schindler SE, Fagan AM.
PMID: 26175713
Front Neurol. 2015 Jun 29;6:142. doi: 10.3389/fneur.2015.00142. eCollection 2015.

Our understanding of the pathogenesis of Alzheimer disease (AD) has been greatly influenced by investigation of rare families with autosomal dominant mutations that cause early onset AD. Mutations in the genes coding for amyloid precursor protein (APP), presenilin 1...

Low-Frequency Oscillations and Control of the Motor Output.

Frontiers in physiology

Lodha N, Christou EA.
PMID: 28261107
Front Physiol. 2017 Feb 14;8:78. doi: 10.3389/fphys.2017.00078. eCollection 2017.

A less precise force output impairs our ability to perform movements, learn new motor tasks, and use tools. Here we show that low-frequency oscillations in force are detrimental to force precision. We summarize the recent evidence that low-frequency oscillations...

NTRK2 expression levels are reduced in laser captured pyramidal neurons from the anterior cingulate cortex in males with autism spectrum disorder.

Molecular autism

Chandley MJ, Crawford JD, Szebeni A, Szebeni K, Ordway GA.
PMID: 26000162
Mol Autism. 2015 May 16;6:28. doi: 10.1186/s13229-015-0023-2. eCollection 2015.

BACKGROUND: The anterior cingulate cortex (ACC) is a brain area involved in modulating behavior associated with social interaction, disruption of which is a core feature of autism spectrum disorder (ASD). Functional brain imaging studies demonstrate abnormalities of the ACC...

Modeling Parkinson's disease in the common marmoset (Callithrix jacchus): overview of models, methods, and animal care.

Laboratory animal research

Yun JW, Ahn JB, Kang BC.
PMID: 26755918
Lab Anim Res. 2015 Dec;31(4):155-65. doi: 10.5625/lar.2015.31.4.155. Epub 2015 Dec 22.

The common marmoset (Callithrix jacchus) is a small-bodied, popular New World monkey and is used widely in reproductive biology, neuroscience, and drug development, due to its comparative ease of handling, high reproductive efficiency, and its unique behavioral characters. In...

Fiber feature map based landmark initialization for highly deformable DTI registration.

Proceedings of SPIE--the International Society for Optical Engineering

Gupta A, Toews M, Janardhana R, Rathi Y, Gilmore J, Escolar M, Styner M.
PMID: 24353392
Proc SPIE Int Soc Opt Eng. 2013 Mar 13;8669. doi: 10.1117/12.2006977.

This paper presents a novel pipeline for the registration of diffusion tensor images (DTI) with large pathological variations to normal controls based on the use of a novel feature map derived from white matter (WM) fiber tracts. The research...

Showing 1 to 12 of 760 entries